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    Home » How Psilocybin Helps with Depression by Rewiring the Brain?
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    How Psilocybin Helps with Depression by Rewiring the Brain?

    WashimBy WashimMarch 4, 2024Updated:April 13, 2024No Comments5 Mins Read
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    Psilocybin is a classic psychedelic that has shown promising results in producing positive therapeutic outcomes in a controlled setting in luxury rehabs. This psychoactive compound is found in certain mushroom species known as magic mushrooms. Psilocybin acts on a specific subtype of serotonin receptors in the brain, which results in alterations to cognition, mood, and perception. These changes in consciousness can enable therapeutic growth. 

    Psilocybin is a popular psychedelic used by many luxury rehabs for treating depression, anxiety, substance dependence, and anxiety. It fosters greater connections between different regions of the brain in people suffering from depression, thus freeing them up from long-held patterns of rumination and excessive self-focus. Psychedelics act therapeutically on the brain to alleviate depression and possibly other psychological conditions marked by fixed patterns of thinking. In this post, we will explore the effect of psilocybin on the brain in detail. 

    Psilocybin experiences significant insight into the various aspects of a patient’s lives and relationships, as well as the sources of the meaning, which includes who they are as a person and how it has shaped their lives. This experience is an important one when treating depression. The research of psilocybin began in the 1940s as a psychedelic medicine for treating various psychiatric conditions like substance use disorders, depression, and alcohol use disorders.

    However, after the 1970s, it was declared a Schedule I drug, and all research and clinical use of psilocybin was shut down. However, in the last ten years, new research into psilocybin and other psychedelics as potential mental health treatments was resumed. And these studies showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms, alcohol use disorder, treatment-resistant depression, tobacco use disorders, anxiety at the end of life or existential distress, and OCD.

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    Research shows that psilocybin treatment reduces connections within brain areas that are tightly connected to depression, including the salience, default mode, and executive networks. It also increases connections to other regions of the brain that have not been well integrated. It makes the patient less emotionally avoidant, and their cognitive functioning gets better. This improvement in depressive symptoms correlates with changes in their brains. 

    Psilocybin and serotonergic psychedelics like Ayahuasca affect the 5-HT2A receptors, which are found in plenty of brain networks that become overactive in depression. One of the hypothesis suggests that these substances briefly disrupt the connections, thus giving them a chance to reform in new ways.  

    However, patients should not attempt self-medication with psilocybin. Medical professionals use regulated doses formulated in a laboratory and also involve extensive psychological support during the process. It is seen that psilocybin works differently from conventional antidepressants, thus making the brain more fluid and flexible as well as less ingrained in the negative thinking patterns associated with depression. Hence, it is a great alternative approach to depression treatments. 

    Psilocybin Ceremonies

    Psilocybin ceremonies have gained much attention in recent years due to their potential to address various mental health conditions. The ceremonial practices involve the consumption of psilocybin-containing mushrooms in a controlled setting. It can treat mental health conditions like PTSD, depression, substance dependency, and trauma. There are also many scientific findings supporting the efficacy of psilocybin ceremonies, as well as the controversial aspects surrounding the legalities of psilocybin.

    Studies have shown that the active compound in a mushroom called psilocybin can have profound effects on brain function, thus leading to altered perceptions, increased emotional openness, and enhanced introspection. Psilocybin ceremonies involve ritualistic elements, therapeutic support, and experience guides in order to create a safe and sacred space for individuals so that individuals can explore their consciousness and emotions.

    Health Benefits of Psilocybin Ceremonies

    Psilocybin ceremonies can offer a range of health benefits. Psilocybin ceremonies can act as catalysts for the personal growth of many people. It enables them to gain new insights, cultivate a greater sense of purpose and meaning, and expand their perspective. They encounter profound experiences during these ceremonies that often lead to self-reflection, introspection, and enhanced self-awareness. It can also enhance the emotional well-being of the person.

    Are There Any Side Effects?

    Psilocybin has mild or intense side effects. The former includes headache, nausea, elevation of heart rate and blood pressure, and changes in body temperature. It may also cause a range of psychological reactions that are challenging for some people to include. These include paranoia, anxiety, and disorientation. Also, patients who have a family history may be at increased risk for experiencing prolonged episodes of psychosis. 

    How Does Psilocybin Therapy Work?

    Administering psilocybin involves an intense psychotherapeutic preparation before taking the substance, which involves being supported during an eight-hour session with two therapists present the entire time. The patient and therapists would also engage in integration sessions to explore how to translate the experience. It has a therapeutic approach and is not just about taking pills to treat symptoms. It has specific intentions behind it.  

    Takeaway

    Despite the controversies surrounding it, psilocybin has emerged as a promising treatment for depression, anxiety, and dependency. Hence, many rehab centers employ psilocybin ceremonies in their treatment plans.

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